• Product Code: XNS120
  • Availability: In Stock
  • From 14.90€

Capsules 50mg

  • 5-HTP

What is 5-HTP?

5-HTP or 5-hydroxytryptophan is a chemical byproduct of the amino acid L-tryptophan,  typically found in common household ingredients such as milk, potatoes, pumpkin, sunflower seeds or chicken. For commercial production the plant griffonia simplicifolia is used for 5-HTP extraction due to its high concentration in this plant. In the central nervous system 5-HTP increases the production of the neurotransmitter serotonin. 

Serotonin carries messages between nerve cells in your central nervous system (brain) and throughout your peripheral nervous system (body). Essentially these chemical messages tell the parts of your body how to work. An imbalance of Serotonin therefore leads directly impact mood, alertness, energy and sexual behaviour

5-HTP used to be prescribed to patients suffering from anxiety, mood swings, depression and even aggression. Meanwhile other and more advanced drugs for depression were released where a prescription is necessary. Therefore 5-HTP is now considered a dietary supplement for which you do not need a prescription in most countries. 

A healthy amount of 5-HTP can curb your appetite, which is why some people use it to reduce obesity. Furthermore, 5-HTP can be tried to alleviate sleep disorders, hot flashes, migraine or fibromyalgia (functional pain syndrome), especially in people who are in menopause, although there is not sufficient research that underlines theses statements..

5-HTP Effects

  • Anxiety relief
  • Antidepressant
  • Control moodswings
  • Reduce aggression
  • Alleviate Sleep Disorders


Capsules should be taken with 250ml of liquid of your choice.


Most sources suggest, one of which is the University of Maryland Medical Center, not to consume more than 50 to 300mg of 5-HTP per day. 

Compound Structure

Chemical Name
2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
Molecular Formula
Molecular Weight
220.228 g/mol
EC Number


5-HTP can be combined with L-Tyrosine or Noopept. In a possible combination, it is best to first combine one preparation and gradually add another. 

Combination with supplements or medicine that increase serotonin levels is not recommended as 5-HTP itself increases serotonin already.

Risks & Side effects

Due to the mechanism of action, high dosages 5-HTP can lead to indigestion such as abdominal pain, bloating, heartburn, flatulence and nausea, which can be prevented by administering a lower dosage. An overdose of 5-HTP can trigger the serotonin syndrome, which in turn can lead to muscle twitching, nervousness, chills, sweating and tremors. Should such side effects occur, a doctor should be consulted immediately.


5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology - View Publication 
Effects of Serotonin and Slow-release 5-HTP on Gastrointestinal Motility in a Mouse Model of Depression - View Publication

Tags: depression, pain, anxiety, sleep disorder

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